Abstract: 
Immune dysregulation, such as in autoimmunities (e.g., lupus) and immunodeficiencies (e.g., HIV), reflects an imbalance in the production of cytokines such as TNF-α (inflammation) and IFN-γ (activation), requiring more precise therapies than conventional ones, limited by nonspecific effects. Quantum biology suggests that quantum coherence can modulate cellular processes, but its application to human immunology is unexplored. This study proposes Quantum Immune Modulation Therapy (TQMI), using electromagnetic f ields — NMR (5 T) and lasers (10¹² W/cm²) - to induce coherence in TCR/BCR receptors, rebalancing immune responses. We simulated 5,000 virtual lymphocytes for 48 hours on an Intel i5 computer with 16 GB of RAM and RTX 3050 GPU, in Python 3.9, with the objectives of: (1) evaluating the effects on TNF-α reduction and IFN-γ increase, (2) predicting results via neural networks, and (3) proposing experimental validation.
 
Cite this article

Francisco José Gonçalves Figueiredo¹, Italo Rossi Roseno Martins¹, Natalia Bitu Pinto¹, Rafaelle Cavalcante de Lira¹, Davi Feitoza Pinto Marinho¹, Marco Antonio Prado Nunes². Quantum Human Immune Modulation Therapy: A Computer Simulation. Science Advance (2025). https://doi.org/10.59208/sa-2025-03-22-9